Recurrent Implantation Failure

IVF and ICSI can be very successful treatment methods. However, some women either fail to conceive despite a number of transfers of apparently good embryos or they conceive but the pregnancy fails to develop into a healthy baby. There are various biological reasons why these two circumstances may be related, leading to potential therapies.

In women with “recurrent implantation failure” in IVF/ICSI treatment cycles, there is some support for several treatment strategies although the available evidence is limited for many of them due to a lack of suitably large studies. With the exception of the ‘endometrial scratch’ procedure the evidence for such interventions including intralipid infusions, Clexane, steroids and laser assisted hatching is lacking.